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Malaria Methods and Protocols

Autore: Denise L. Doolan

Numero di pagine: 606

The Plasmodium spp. parasite was identified as the causative agent of malaria in 1880, and the mosquito was identified as the vector in 1897. Despite subsequent efforts focused on the epidemiology, cell biology, immunology, molecular biology, and clinical manifestations of malaria and the Plasmodium parasite, there is still no licensed vaccine for the prevention of malaria. Physical barriers (bed nets, window screens) and chemical prevention methods (insecticides and mosquito repellents) intended to interfere with the transmission of the disease are not highly effective, and the profile of resistance of the parasite to chemoprophylactic and chemotherapeutic agents is increasing. The dawn of the new millennium has seen a resurgence of interest in the disease by government and philanthropic organizations, but we are still faced with compl- ities of the parasite, the host, and the vector, and the interactions among them. Malaria Methods and Protocols offers a comprehensive collection of protocols describing conventional and state-of-the-art techniques for the study of malaria, as well as associated theory and potential problems, written by experts in the field. The major themes...

World Malaria Report 2009

Autore: World Health Organization

Numero di pagine: 201

"Half of the world's population is at risk of malaria, and an estimated 243 million cases led to nearly 863 000 deaths in 2008. The advent of long-lasting insecticidal nets and artemisinin-based combination therapy, plus a revival of support for indoor residual spraying of insecticide, presents a new opportunity for large-scale malaria control. The World malaria report 2009 describes the global distribution of cases and deaths, how WHO-recommended control strategies have been adopted and implemented in endemic countries, sources of funding for malaria control, and recent evidence that prevention and treatment can alleviate the burden of disease."--Publisher's description.

Malaria

Autore: Mary M. Stevenson

Numero di pagine: 182

The purpose of this book is to analyze and determine how a host responds to a blood stage malaria infection. It focuses on strategies for anti-malarial vaccination, genetic control of host resistance to malaria, and the contribution of the host genetic background to resistance or susceptibility to malaria. This book is an important reference work for anyone who studies the field of microbiology, immunology, or parasitology.

Malaria

Autore: Bernard A. Marcus

Numero di pagine: 120

Describes the disease malaria, including history, cause, treatment breakthroughs, vaccines, and the impact of global climate change on outbreak patterns.

Malaria in South Asia

Autore: Rais Akhtar , Ashok K. Dutt , Vandana Wadhwa

Numero di pagine: 265

Malaria is one of the most widespread and devastating infectious diseases in the world. More than half the world population residing in over 100 countries is at risk of infection from this vector-borne disease. An estimated 250–500 million mal- ial cases occur each year, resulting in nearly one million deaths, the overwhelming majority of which are children. Because of the magnitude of the associated fata- ties, development experts consider malaria a ‘silent tsunami,’ comparing its death toll to the Indian Ocean tsunami (IOT) that ravaged several countries of South and Southeast Asia on December 26, 2004. That tsunami killed some 300,000 people (including children) at once. Globally, malarial deaths account for about 9% of all childhood deaths each year. However, with malaria more than most fatal d- eases, mortality is a small fraction of morbidity. Malaria is a debilitating disease, particularly for the adult population. In addition to children, pregnant women and migrating populations are most v- nerable to malaria. Miscarriage, stillbirth, and low birth weight are common among pregnant women who are infected with this disease. Malaria manifests itself through recurrent...

Guidelines for the Treatment of Malaria

Autore: World Health Organization

Numero di pagine: 208

"Malaria case management remains a vital component of the malaria control strategies. This entails early diagnosis and prompt treatment with effective antimalarial medicines. The WHO Guidelines for the treatment of malaria, which were first published in 2006, provide global, evidence-based recommendations on the case management of malaria, targeted mainly at policy-makers at country level, providing a framework for the development of specific and more detailed national treatment protocols that take into account local antimalarial drug resistance patterns and health service capacity in the country. This second edition of the guidelines revisits the recommendations based on updated evidence. The same presentation format from the first edition has been mainly kept based on feedback from the end-users." - p. ix

Malaria

Autore: Paolo Mazzarello

Numero di pagine: 203

Nel 1902 il premio Nobel per la Medicina venne assegnato al medico britannico Ronald Ross «per il suo lavoro sulla malaria». Ma, sulla sola base dei suoi studi, nessuna profilassi contro la malattia sarebbe stata realizzabile. Il riconoscimento escludeva Battista Grassi, il medico lombardo che aveva identificato la zanzara del genere Anopheles responsabile del contagio, descrivendo lo sviluppo del parassita nell’insetto e la sua trasmissione all’uomo. Grazie alle proprie ricerche, lo studioso italiano fu il primo a organizzare una profilassi antimalarica scientificamente fondata. Per quale ragione Grassi venne escluso dal Nobel che avrebbe dovuto condividere con Ross? Basandosi sugli studi storici più recenti e sulla documentazione esistente, Malaria racconta l’incredibile congiura ordita contro Grassi, guidata dallo stesso Ross e dal grande microbiologo tedesco Robert Koch, della quale fecero inconsapevolmente parte alcuni colleghi italiani. Proprio nelle cruciali settimane in cui si sarebbe decisa l’assegnazione del premio, infatti, non lo appoggiarono o addirittura lo accusarono di plagio. Alla base dell’accanimento dei colleghi vi furono diverse ragioni, non...

Traditional Medicinal Plants and Malaria

Autore: Merlin Willcox , Gerard Bodeker , Philippe Rasoanaivo , Jonathan Addae-kyereme

Numero di pagine: 541

Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala

Environmental Factors and Malaria Transmission Risk

Autore: Yazoumé Yé

Numero di pagine: 176

The fifth Millennium Development target of reducing infant mortality by two thirds by the year 2015 can only be achieved if mortality due to malaria is significantly reduced.This book addresses this issue by developing an innovative methodology and modeling used to assess local scale malaria risk using environmental factors. The detailed description of this pioneering methodology enables scientists to replicate the study elsewhere in different settings.

Water-related Environmental Factors and Malaria Transmission in Mahi Kadana, Gujarat, India

Numero di pagine: 24

Intensifying the Fight Against Malaria

Numero di pagine: 150

control in Africa, will intensify its efforts to help more African countries to achieve and sustain large-scale impact on malaria." --Book Jacket.

Molecular Immunological Considerations in Malaria Vaccine Development

Autore: Michael F. Good , Allan J. Saul

Numero di pagine: 282

Some of the world's leading research scientists in the field have contributed to this new book on malaria vaccine development. The book examines various strategies being pursued against the different stages of the parasite (the sporozoite, asexual erythrocytic stages, and sexual stages). It describes vaccines that combat the parasite directly, vaccines aimed at preventing disease, vaccines based on attenuated parasites, and vaccines based on small, carefully defined synthetic peptides. The book provides a compendium of current approaches, lists of preferred antigens, and the results of vaccine trials to date. Molecular immunology involved with both the natural immune response to parasites and with the constraints on inducing immunity are emphasized throughout the book. Views on how vaccines may be tested and then integrated into malaria control programs are also discussed. Molecular Immunological Considerations in Malaria Vaccine Development will be useful for researchers and students in immunology, parasitology, biotechnology, vaccine design, and tropical and public health.

The Linkages Between Agriculture and Malaria: Issues for Policy, Research, and Capacity Strengthening

Autore: Kwadwo Asenso-okyere, Felix A. Asante, Jifar Tarekegn, And Kwaw S. Andam

Numero di pagine: 40

Global malaria control U.S. and multinational investments and implementation challenges.

Autore: Marcia Crosse

Numero di pagine: 57

Progress in Malaria Research

Autore: Lee O. Koning

Numero di pagine: 252

Malaria is an infectious disease that is widespread in tropical and subtropical regions. It infects between 300 and 500 million people every year and causes between one and three million deaths annually, mostly among young children in Sub-Saharan Africa. Malaria is not just a disease commonly associated with poverty, but is also a cause of poverty and a major hindrance to economic development. Malaria is one of the most common infectious diseases and an enormous public health problem. The disease is caused by protozoan parasites of the genus Plasmodium. The most serious forms of the disease are caused by Plasmodium falciparum and Plasmodium vivax, but other related species (Plasmodium ovale and Plasmodium malariae) can also infect humans. This group of human-pathogenic Plasmodium species are usually referred to as malaria parasites. This book presents leading-edge new research in this field.

Malaria; Its Cause and Effects

Autore: Edgar Geer Russell

Numero di pagine: 444

Two Monographs on Malaria and the Parasites of Malarial Fevers

Autore: Ettore Marchiafava , Amico Bignami , New Sydenham Society

Numero di pagine: 492

Regional Guidelines for the Management of Severe Falciparum Malaria in Large Hospitals

Autore: Who Regional Office For South-east Asia

Numero di pagine: 60

In view of heavy burden of malaria and prevalence of drug resistant falciparum malaria in the South-East Asia Region these two parallel guidelines one for small hospitals and another one for large hospitals were developed for use by medical personnel who treat severe malaria patients referred from lower-level health facilities. These guidelines were developed by the WHO Regional Office for South-East Asia and the WHO Collaborating Centre for the Clinical Management of Malaria Faculty of Tropical Medicine Mahidol University Thailand. They are based on a review of current evidence existing WHO guidelines and experience in the management of malaria in the Region.

Medical Geography of Malaria in Madhya Pradesh

Autore: Sarojini Pacholi

Numero di pagine: 176

Medical Geography is a scientific discipline which links medicine with Geography. It is concerned with systematic study of spatial distribution of diseases in the backdrop of geographical conditions in order to find out answers to â€˜whereâ€™ and â€˜whyâ€™ of diseases. In India no disease has taken toll of such a large number of human beings as Malaria. Moreover, it steps the vitality of millions of people and forces them towards poverty.

Handbook of geographical and historical pathology v. 1 1883

Autore: August Hirsch

Numero di pagine: 732

The Johns Hopkins Hospital Reports

Autore: Johns Hopkins Hospital

Numero di pagine: 556

The Prevention of Malaria

Autore: Sir Ronald Ross

Numero di pagine: 760

Twentieth Century Practice: Malaria and micro-organisms

Autore: Thomas Lathrop Stedman

Numero di pagine: 880

Medical News and Abstract

Numero di pagine: 840

Records of the Malaria Survey of India

Numero di pagine: 740

The American Journal of the Medical Sciences

Numero di pagine: 774

Malaria and Rome

Autore: Robert Sallares

Numero di pagine: 358

Malaria and Rome is the first comprehensive study of malaria in ancient Italy since the research of the distinguished Italian malariologist Angelo Celli in the early twentieth century. It demonstrates the importance of disease patterns and history in understanding the demography of ancient populations. Robert Sallares argues that malaria became increasingly prevalent in Roman times in central Italy as a result of ecological change and alterations to the physical landscapesuch as deforestation. Making full use of contemporary sources and comparative material from other periods, he shows that malaria had a significant effect on mortality rates in certain regions of Roman Italy.Robert Sallares incorporates all the important advances made in many relevant fields since Celli's time. These include recent geomorphological research on the evolution of the coastal environments of Italy that were notorious for malaria in the past, biomolecular research on the evolution of malaria, ancient DNA as a new source of evidence for malaria in antiquity, the differentiation of mosquito species that permits understanding of the phenomenon of anophelism without malaria (where theclimate is optimal for ...

Tanzania HIV/AIDS and Malaria Indicator Survey, 2007-08: HIV

Numero di pagine: 306

The Journal of the National Malaria Society

Autore: National Malaria Society (u.s.)

Numero di pagine: 452

Includes minutes (sometimes called Proceedings) of the 24th-33rd annual meeting of the Society.

Environmental Change and Malaria Risk

Autore: Willem Takken , Willem Jozef Meine Martens , Robert J. Bogers

Numero di pagine: 172

This book reflects the discussions of leading scientists on the potential impact of global change on malaria and other vector-borne diseases. The book makes clear that environmental change, more than climate change, is the driving force behind the observed changes in disease risk. The rapid spread of blue tongue, another highly infectious vector-borne disease, illustrates what might happen if the world looks on unguarded.

Malaria in Pregnancy

Autore: Makiva Tuni

Numero di pagine: 18

An Evaluation of the Socio-economic Factors Associated with Malaria in Zambia

Autore: Naawa Sipilanyambe

Numero di pagine: 88

Entomological Field Techniques for Malaria Control: Learner's guide

Autore: World Health Organization

Numero di pagine: 84

A practical training module on entomological field techniques for malaria control presented in two separately bound parts. The first, addressed to learners, provides step-by-step instructions in the field, and work needed to secure comprehensive information about the mosquito population in a given area. Information is presented in a series of 13 illustrated learning units, moving from the simplest collecting techniques that can be practiced in the laboratory to more sophisticated procedures that must be undertaken in the field. Techniques covered include hand collection methods, indoor collection after pyrethrin spraying, direct catches of mosquitoes from animal and human bait, and collection of larvae and pupae from breeding sites. Other units help readers learn how to identify species at all stages of the life cycle, keep accurate records, and preserve and transport specimens under strictly controlled conditions. The need to gain the cooperation of the community is also thoroughly explained. The second part, addressed to tutors, offers practical advice on the organization and running of training courses. Like the first part, the Tutor's Guide is divided into a series of learning ...