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This Research Topic is the second volume of the "Community Series In Mental-Health-Related Stigma and Discrimination: Prevention, Role, and Management Strategies". Please see the first volume here. Despite the tremendous progress and successes achieved in diagnostics, therapy, and rehabilitation in psychiatry over the past few decades, the stigma towards mental health patients, their relatives and caregivers, and healthcare professionals is still present. Social stigma, in particular, represents a major obstacle to maintaining adequate mental health care. This increases reluctance to seek help delays patients' diagnosis and limits their compliance and adherence to treatment. In the long term, this reduces psychiatric rehabilitation effectiveness and causes a burden to healthcare providers and society alike. The main goal of this Research Topic is to evaluate the impact and role of stigma, in all its forms, on individuals with psychiatric disorders, their caregivers, and mental health providers.